Sexy Daria is an alternate universe created by Shiva in which Daria Morgendorffer made the choice to use her looks to full advantage when she was younger, thus becoming the most popular girl in Highland and now in Lawndale. The boys love her, the girls either hate her, want to be her, or both. Her family life, however, is even worse than in canon - and Quinn fumes at being completely outflanked in popularity.
In terms of real friends, Daria quickly bonds with artist Jane Lane and the other new girl Scarlett LeVey, who comes with a few surprises. Skyler Feldman appears later on as her first significant boyfriend.